|
|
| Nomenclature |
|
Symbol:
|
Gdnftm2Bbd
|
|
Name:
|
glial cell line derived neurotrophic factor;
targeted mutation 2, Mariano Barbacid
|
|
MGI ID: |
MGI:2136845 |
|
Synonyms: |
Gdnf-, GDNF/neo |
|
Gene:
|
Gdnf
Location:
Chr15:7811011-7837575 bp, + strand
Genetic Position: Chr15,
3.8 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:33809
|
|
Parent Cell Line:
| CJ7 (ES Cell) |
|
Strain of Origin:
|
129S1/Sv-Oca2+ Tyr+ Kitl+
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Replacement of exon 2 with a neomycin cassette. (J:33809)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Gdnf Mutation:
|
4 strains or lines available |
|
| References |
|
Original: |
J:33809
Sanchez MP et al.,
"Renal agenesis and the absence of enteric neurons in mice lacking GDNF."
Nature 1996 Jul 4;382(6586):70-3
|
|
All: |
8 reference(s)
|
|
Analysis Tools
