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| Nomenclature |
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Symbol:
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Pitx2tm1Jfm
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Name:
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paired-like homeodomain transcription factor 2;
targeted mutation 1, James F Martin
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MGI ID: |
MGI:2136268 |
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Synonyms: |
delta abcnull, pitx2hd |
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Gene:
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Pitx2
Location:
Chr3:129199878-129219591 bp, + strand
Genetic Position: Chr3,
57.84 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:57674
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Parent Cell Line:
| AK7 (ES Cell) |
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Strain of Origin:
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129S4/SvJaeSor
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance cassette replaced exon 5 and part of exon 6, which encodes the homeobox domain. (J:57674)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Expression |
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:57674
Lu MF et al.,
"Function of Rieger syndrome gene in left-right asymmetry and craniofacial development."
Nature 1999 Sep 16;401(6750):276-8
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All: |
13 reference(s)
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Analysis Tools
