Myf5tm3(cre)Sor
Targeted Allele Detail
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| Nomenclature |
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Symbol:
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Myf5tm3(cre)Sor
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Name:
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myogenic factor 5;
targeted mutation 3, Philippe Soriano
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MGI ID: |
MGI:2135565 |
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Synonyms: |
Mif5-Cre, Myf5Cre |
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Gene:
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Myf5
Location:
Chr10:107482908-107486134 bp, - strand
Genetic Position: Chr10,
55.95 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:65301
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Parent Cell Line:
| AK7 (ES Cell) |
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Strain of Origin:
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129S4/SvJaeSor
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: A cre cDNA was inserted between a SacI site and a KpnI site in the 5'UTR of the Myf5 gene. An adjacent loxP-flanked neomycin cassette was removed by Cre- mediated recombination. (J:65301)
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Recombinase activity
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Activity in:
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adipose tissue,
alimentary system,
branchial arches,
cardiovascular system,
cavities & their linings,
embryo-other,
endocrine system,
head,
hemolymphoid system,
integumental system,
limbs,
liver & biliary system,
mesenchyme,
muscle,
nervous system,
postnatal-other,
renal & urinary system,
reproductive system,
respiratory system,
sensory organs,
skeletal system,
tail
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Driver:
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Myf5
Summary of all recombinase alleles
driven by Myf5.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:65301
Tallquist MD et al.,
"Early myotome specification regulates PDGFA expression and axial skeleton development"
Development 2000 Dec;127(23):5059-70
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All: |
38 reference(s)
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Analysis Tools
