Lyz2tm1(cre)Ifo
Targeted Allele Detail
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| Nomenclature |
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Symbol:
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Lyz2tm1(cre)Ifo
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Name:
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lysozyme 2;
targeted mutation 1, Irmgard Forster
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MGI ID: |
MGI:1934631 |
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Synonyms: |
LC, LCre, Lys-cre, LysCre, lysM/cre, LysMcre, LysMCre, LysMCre, LysM Cre, LysM-Cre, Lystm1(cre)Ifo, Lyz-cre, LyzCre |
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Gene:
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Lyz2
Location:
Chr10:117277541-117282272 bp, - strand
Genetic Position: Chr10,
65.34 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:67924
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: An NLS-cre gene was inserted into the endogenous ATG start site of the gene. An frt-flanked neomycin cassette was removed in ES cells via Flp-mediated recombination prior to production of chimeric mice. (J:67924)
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Recombinase activity
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Activity in:
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alimentary system,
cardiovascular system,
hemolymphoid system,
liver & biliary system,
nervous system,
reproductive system,
respiratory system
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Not detected in:
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adipose tissue,
embryo-other,
endocrine system,
extraembryonic component,
integumental system,
muscle,
postnatal-other,
renal & urinary system,
sensory organs,
skeletal system
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Driver:
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Lyz2
Summary of all recombinase alleles
driven by Lyz2.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:67924
Clausen BE et al.,
"Conditional gene targeting in macrophages and granulocytes using LysMcre mice."
Transgenic Res 1999 Aug;8(4):265-77
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All: |
381 reference(s)
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Analysis Tools
