|
|
| Nomenclature |
|
Symbol:
|
Shhtm1Amc
|
|
Name:
|
sonic hedgehog;
targeted mutation 1, Andrew P McMahon
|
|
MGI ID: |
MGI:1934261 |
|
Synonyms: |
Shh-, Shhn |
|
Gene:
|
Shh
Location:
Chr5:28456815-28467101 bp, - strand
Genetic Position: Chr5,
14.39 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:50050
|
|
Parent Cell Line:
| R1 (ES Cell) |
|
Strain of Origin:
|
(129X1/SvJ x 129S1/Sv)F1-Kitl+
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
A neomycin cassette replaced exon 2 and portions of the flanking intronic sequences. (J:50050)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:50050
St-Jacques B et al.,
"Sonic hedgehog signaling is essential for hair development."
Curr Biol 1998 Sep 24;8(19):1058-68
|
|
All: |
55 reference(s)
|
|
Analysis Tools
