|
|
| Nomenclature |
|
Symbol:
|
Pitx1tm1Rsd
|
|
Name:
|
paired-like homeodomain transcription factor 1;
targeted mutation 1, Michael G Rosenfeld
|
|
MGI ID: |
MGI:1934200 |
|
Gene:
|
Pitx1
Location:
Chr13:55825054-55836192 bp, - strand
Genetic Position: Chr13,
30.06 cM
|
|
Mutation origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:53310
|
|
Parent Cell Line:
| R1 (ES Cell) |
|
Strain of Origin:
|
(129X1/SvJ x 129S1/Sv)F1-Kitl+
|
|
Mutation description |
|
Allele
Type: | |
Targeted (Reporter) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: The sequences encoding the homeodomain and most of the 3' coding sequence of this gene were replaced with a lacZ/neo-derived cassette via homologous recombination. (J:53310)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Pitx1 Mutation:
|
1 strain or line available |
|
| References |
|
Original: |
J:53310
Szeto DP et al.,
"Role of the Bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development."
Genes Dev 1999 Feb 15;13(4):484-94
|
|
All: |
3 reference(s)
|
|