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| Nomenclature |
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Symbol:
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Cdkn1ctm1Kat
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Name:
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cyclin-dependent kinase inhibitor 1C (P57);
targeted mutation 1, Katsuhiko Takahashi
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MGI ID: |
MGI:1933758 |
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Synonyms: |
p57-, p57Kip2(-) |
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Gene:
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Cdkn1c
Location:
Chr7:143458350-143461050 bp, - strand
Genetic Position: Chr7,
88.22 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:61190
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Replacement of the entire coding region, including exons 1, 2, 3 and part of exon 4 with a neomycin cassette. (J:61190)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cdkn1c Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:61190
Takahashi K et al.,
"Mice lacking a CDK inhibitor, p57(Kip2), exhibit skeletal abnormalities and growth retardation"
J Biochem 2000 Jan;127(1):73-83
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All: |
7 reference(s)
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Analysis Tools
