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| Nomenclature |
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Symbol:
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Atmtm1Pmc
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Name:
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ataxia telangiectasia mutated homolog (human);
targeted mutation 1, Peter J McKinnon
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MGI ID: |
MGI:1933746 |
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Synonyms: |
Atm- |
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Gene:
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Atm
Location:
Chr9:53439149-53536740 bp, - strand
Genetic Position: Chr9,
29.12 cM, cytoband C-D
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:47752
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin gene interrupts exon 57 and replaces exon 58. This region corresponds to a region deleted in some human AT deficiency cases. (J:47752)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Atm Mutation:
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29 strains or lines available |
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| References |
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Original: |
J:47752
Herzog KH et al.,
"Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system."
Science 1998 May 15;280(5366):1089-91
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All: |
26 reference(s)
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Analysis Tools
