Foxg1tm1(cre)Skm
Targeted Allele Detail
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| Nomenclature |
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Symbol:
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Foxg1tm1(cre)Skm
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Name:
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forkhead box G1;
targeted mutation 1, Susan K McConnell
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MGI ID: |
MGI:1932522 |
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Synonyms: |
BF1-cre, Foxg1-, Foxg1Cre, Foxg1-Cre, Foxg1:Cre, FoxG1Cre, Foxg1KiCre, TgH(Foxg1-Cre)1Skm |
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Gene:
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Foxg1
Location:
Chr12:49382693-49386856 bp, + strand
Genetic Position: Chr12,
21.78 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:62916
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Parent Cell Line:
| HM-1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd-Hprtb-m3
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Most of the coding region was replaced with a cre gene and a neomycin cassette. The cre gene sequence was fused in-frame following the first 13 codons of the gene. The endogenous promoter is active in telencephalon, anterior optic vesicle, otic vesicle, facial and head ectoderm, olfactory epithelium, mid-hindbrain junction and pharyngeal pouches. (J:62916)
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Inheritance: | |
Recessive |
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Cre mediated recombination was demonstrated in 3 reporter mouse lines in the following tissues: telencephalon, anterior optic vesicle, otic vesicle, facial and head ectoderm, olfactory epithelium, mid-hindbrain junction, and pharyngeal pouches.
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| References |
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Original: |
J:62916
Hebert JM et al.,
"Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures."
Dev Biol 2000 Jun 15;222(2):296-306
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All: |
124 reference(s)
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Analysis Tools
