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| Nomenclature |
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Symbol:
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F9tm1Dws
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Name:
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coagulation factor IX;
targeted mutation 1, Darrel W Stafford
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MGI ID: |
MGI:1932297 |
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Synonyms: |
factor IX-knockout, FIX(-), HB |
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Gene:
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F9
Location:
ChrX:59999464-60030759 bp, + strand
Genetic Position: ChrX,
33.5 cM, cytoband A6-A7
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:44497
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Parent Cell Line:
| E14TG2a (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 1, 2 and 3 are replaced by a neomycin/hprt minigene cassette. No mRNA was detected in hemizygous male mice as assayed by RT-PCR analysis. (J:44497)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:44497
Lin HF et al.,
"A coagulation factor IX-deficient mouse model for human hemophilia B."
Blood 1997 Nov 15;90(10):3962-6
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All: |
13 reference(s)
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Analysis Tools
