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| Nomenclature |
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Symbol:
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Mmp9tm1Tvu
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Name:
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matrix metallopeptidase 9;
targeted mutation 1, Thiennu H Vu
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MGI ID: |
MGI:1932294 |
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Synonyms: |
Gelatinase B-Null, GelB-, Mmp9-, MMP-9-, MMP9-, MMP-9KO, MMP-9 KO |
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Gene:
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Mmp9
Location:
Chr2:164940780-164955850 bp, + strand
Genetic Position: Chr2,
85.27 cM, cytoband H1-H2
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:47297
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Parent Cell Line:
| Other (see notes) (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Part of exon 2 and all of intron 2 were replaced with a cassette containing the neomycin resistance gene driven by a PGK promoter. (J:47297)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
ES cell line = ZW4.
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| References |
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Original: |
J:47297
Vu TH et al.,
"MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes."
Cell 1998 May 1;93(3):411-22
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All: |
176 reference(s)
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Analysis Tools
