|
|
| Nomenclature |
|
Symbol:
|
F9tm1Emg
|
|
Name:
|
coagulation factor IX;
targeted mutation 1, Erlinda M Gordon
|
|
MGI ID: |
MGI:1932244 |
|
Synonyms: |
F. IX |
|
Gene:
|
F9
Location:
ChrX:59999464-60030759 bp, + strand
Genetic Position: ChrX,
33.5 cM, cytoband A6-A7
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:48501
|
|
Parent Cell Line:
| CCE/EK.CCE (ES Cell) |
|
Strain of Origin:
|
129S/SvEv-Gpi1c
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A neomycin cassette replaced 3.2 kb of sequence spanning exons g and h. Neither RT-PCR and Northern blot analyses detected mRNA in homozygous mutant mice. (J:48501)
|
|
Inheritance: | |
Recessive |
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any F9 Mutation:
|
1 strain or line available |
|
| References |
|
Original: |
J:48501
Kundu RK et al.,
"Targeted inactivation of the coagulation factor IX gene causes hemophilia B in mice."
Blood 1998 Jul 1;92(1):168-74
|
|
All: |
1 reference(s)
|
|
Analysis Tools
