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| Nomenclature |
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Symbol:
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Myl1tm1(cre)Sjb
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Name:
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myosin, light polypeptide 1;
targeted mutation 1, Steven J Burden
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MGI ID: |
MGI:1931135 |
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Synonyms: |
Mlc1f-cre, mlccre, MLC-Cre, Mlcf-cre |
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Gene:
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Myl1
Location:
Chr1:66924295-66945404 bp, - strand
Genetic Position: Chr1,
33.71 cM
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Skeletal muscle analysis of Tfamtm1Lrsn/Tfamtm1Lrsn Myl1tm1(cre)Sjb/Myl1+ mice
Show the 2 image(s) involving this allele.
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:67675
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: Insertion of an NLS-cre gene into exon 1, immediately upstream of the initiator ATG. An adjacent lox-P flanked neomycin cassette was removed by Cre mediated recombination in the final allele. (J:67675)
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Recombinase activity
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Activity:
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 Tissue activity of this recombinase allele
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Driver:
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Myl1
Summary of all recombinase alleles
driven by Myl1.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Myl1 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:67675
Bothe GW et al.,
"Selective expression of Cre recombinase in skeletal muscle fibers."
Genesis 2000 Feb;26(2):165-6
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All: |
21 reference(s)
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