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| Nomenclature |
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Symbol:
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Hesx1tm1Icar
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Name:
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homeobox gene expressed in ES cells;
targeted mutation 1, Iain C A F Robinson
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MGI ID: |
MGI:1931124 |
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Synonyms: |
Hesx1- |
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Gene:
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Hesx1
Location:
Chr14:27000362-27002329 bp, + strand
Genetic Position: Chr14,
16.09 cM, cytoband A3-B
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:47920
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Deletion of the entire coding region and replacement with a neomycin cassette. (J:47920)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Hesx1 Mutation:
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0 strains or lines available |
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| References |
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Original: |
J:47920
Dattani MT et al.,
"Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse."
Nat Genet 1998 Jun;19(2):125-33
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All: |
7 reference(s)
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Analysis Tools
