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| Nomenclature |
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Symbol:
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Csf2tm1Ard
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Name:
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colony stimulating factor 2 (granulocyte-macrophage);
targeted mutation 1, Ashley R Dunn
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MGI ID: |
MGI:1930997 |
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Synonyms: |
CSF-2o, GM-, GM-CSF- |
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Gene:
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Csf2
Location:
Chr11:54247271-54249667 bp, - strand
Genetic Position: Chr11,
32.13 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:18747
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 1 and 2 and flanking intronic sequence was replaced by a LacZ gene, human beta globin gene 3' untranslated and poly(A) sequences and a neomycin cassette. (J:18747)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Csf2 Mutation:
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11 strains or lines available |
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| References |
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Original: |
J:18747
Stanley E et al.,
"Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology."
Proc Natl Acad Sci U S A 1994 Jun 7;91(12):5592-6
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All: |
38 reference(s)
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