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| Nomenclature |
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Symbol:
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Ifngr2tm1Pbro
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Name:
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interferon gamma receptor 2;
targeted mutation 1, Paul B Rothman
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MGI ID: |
MGI:1930965 |
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Synonyms: |
IFN-gammaR2 -, IFNgammaRBnull, Ifngr2tm1Cmb |
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Gene:
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Ifngr2
Location:
Chr16:91547072-91565169 bp, + strand
Genetic Position: Chr16,
53.07 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:48016
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Parent Cell Line:
| W9.5/W95 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
| |
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Replacement of the second coding exon with a neomycin gene. (J:48016)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:48016
Lu B et al.,
"Targeted disruption of the interferon-gamma receptor 2 gene results in severe immune defects in mice."
Proc Natl Acad Sci U S A 1998 Jul 7;95(14):8233-8
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All: |
13 reference(s)
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Analysis Tools
