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Bdnftm1Par
Targeted Allele Detail

Nomenclature
Symbol: Bdnftm1Par
Name: brain derived neurotrophic factor; targeted mutation 1, Luis Parada
MGI ID: MGI:1929986
Synonyms: BDNF-, BNDFtm1-LT
Gene: Bdnf   Location: Chr2:109674700-109727007 bp, + strand    Genetic Position: Chr2, 56.63 cM
Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:44286
Parent Cell Line: CJ7 (ES Cell)
Strain of Origin: 129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:   Targeted (knock-out)
Mutation:   Insertion
    A neomycin cassette was inserted into a Sal1 site in the single coding exon of the gene. (J:44286)
Inheritance:   Recessive
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bdnf Mutation: 8 strains or lines available
References
Original: J:44286 Liebl DJ et al., "Absence of sensory neurons before target innervation in brain-derived neurotrophic factor-, neurotrophin 3-, and TrkC-deficient embryonic mice." J Neurosci 1997 Dec 1;17(23):9113-21
All: 26 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/08/2013
MGI 5.13
The Jackson Laboratory