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| Nomenclature |
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Symbol:
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Tg(Trp53R172H)8512Jmr
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Name:
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transgene insertion 8512, Jeffrey Rosen
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MGI ID: |
MGI:1929642 |
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Synonyms: |
172R-H, p53-172H, p53(R172H), Wap-p53R172H |
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Transgene:
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Tg(Trp53R172H)8512Jmr
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene contains the rat whey acidic protein promoter and an allele of the mouse Trp53 mini-gene that carries a point mutation in codon 172 (CGC->CAC; Arg172His). (J:46426)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
On an FVB/N background transgenic mice express TRP53 with both dominant-negative and a gain-of function properties.
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| References |
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Original: |
J:46426
Li B et al.,
"A transgenic mouse model for mammary carcinogenesis."
Oncogene 1998 Feb 26;16(8):997-1007
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All: |
11 reference(s)
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Analysis Tools
