|
|
| Nomenclature |
|
Symbol:
|
Nkx3-1tm1Hha
|
|
Name:
|
NK-3 transcription factor, locus 1 (Drosophila);
targeted mutation 1, Hans-Henning Arnold
|
|
MGI ID: |
MGI:1928654 |
|
Synonyms: |
Nkx3.1 - |
|
Gene:
|
Nkx3-1
Location:
Chr14:69190638-69194662 bp, + strand
Genetic Position: Chr14,
36.02 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:63764
|
|
Parent Cell Line:
| J1 (ES Cell) |
|
Strain of Origin:
|
129S4/SvJae
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (Reporter) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A lacZ-PGK-neomycin resistance cassette replaced most of exon 2, which encodes the entire homeobox domain. (J:63764)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Nkx3-1 Mutation:
|
5 strains or lines available |
|
| References |
|
Original: |
J:63764
Schneider A et al.,
"Targeted disruption of the nkx3.1 gene in mice results in morphogenetic defects of minor salivary glands: parallels to glandular duct morphogenesis in prostate"
Mech Dev 2000 Jul;95(1-2):163-74
|
|
All: |
2 reference(s)
|
|
Analysis Tools
