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| Nomenclature |
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Symbol:
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Nrg1tm1Cbm
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Name:
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neuregulin 1;
targeted mutation 1, Carmen Birchmeier
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MGI ID: |
MGI:1928489 |
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Synonyms: |
neuregulindelta7-9, Nrg- |
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Gene:
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Nrg1
Location:
Chr8:31818028-31918203 bp, - strand
Genetic Position: Chr8,
18.75 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:29971
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Parent Cell Line:
| E14.1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance gene replaces exons 7, 8 and 9, which encode the carboxy-terminus of the EGF domain of all known Ngf1 variants. (J:29971)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Nrg1 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:29971
Meyer D et al.,
"Multiple essential functions of neuregulin in development [see comments] [published erratum appears in Nature 1995 Dec 14;378(6558):753]"
Nature 1995 Nov 23;378(6555):386-90
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All: |
19 reference(s)
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Analysis Tools
