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| Nomenclature |
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Symbol:
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Grin1tm2Stl
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Name:
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glutamate receptor, ionotropic, NMDA1 (zeta 1);
targeted mutation 2, Susumu Tonegawa
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MGI ID: |
MGI:1928279 |
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Synonyms: |
Flox-B, floxed-NR1, fNR1, NR1flox |
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Gene:
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Grin1
Location:
Chr2:25291181-25319187 bp, - strand
Genetic Position: Chr2,
17.14 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:37457
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Insertion of loxP sites flanking the entire transmembrane region (exons 11-21 through the 3' end of the gene). (J:37457)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:37457
Tsien JZ et al.,
"The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory [see comments]"
Cell 1996 Dec 27;87(7):1327-38
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All: |
45 reference(s)
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