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| Nomenclature |
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Symbol:
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Grin1tm1Stl
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Name:
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glutamate receptor, ionotropic, NMDA1 (zeta 1);
targeted mutation 1, Susumu Tonegawa
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MGI ID: |
MGI:1928270 |
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Synonyms: |
NMDAR1-, NR1- |
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Gene:
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Grin1
Location:
Chr2:25291181-25319187 bp, - strand
Genetic Position: Chr2,
17.14 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:17384
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance cassette replaced a 2.4kb genomic fragment containing exons encoding four transmembrane domains. (J:17384)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Grin1 Mutation:
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10 strains or lines available |
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| References |
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Original: |
J:17384
Li Y et al.,
"Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice."
Cell 1994 Feb 11;76(3):427-37
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All: |
15 reference(s)
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Analysis Tools
