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| Nomenclature |
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Symbol:
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Sfpi1tm1Ram
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Name:
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SFFV proviral integration 1;
targeted mutation 1, Richard A Maki
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MGI ID: |
MGI:1927876 |
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Synonyms: |
PU.1 (-) |
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Gene:
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Sfpi1
Location:
Chr2:91082390-91115756 bp, + strand
Genetic Position: Chr2,
50.44 cM, cytoband E3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:36473
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Insertion of a neomycin gene into exon 5, which encodes the DNA binding domain. (J:36473)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Sfpi1 Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:36473
McKercher SR et al.,
"Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities."
EMBO J 1996 Oct 15;15(20):5647-58
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All: |
16 reference(s)
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Analysis Tools
