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| Nomenclature |
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Symbol:
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Fgf10tm1Wss
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Name:
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fibroblast growth factor 10;
targeted mutation 1, W Scott Simonet
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MGI ID: |
MGI:1927833 |
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Synonyms: |
Fgf-10-, Fgf10-, fgf10neo |
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Gene:
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Fgf10
Location:
Chr13:118669791-118792115 bp, + strand
Genetic Position: Chr13,
67.14 cM, cytoband A3-A4
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Palatal abnormalities in Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn and Fgf10tm1Wss/Fgf10tm1Wss mice
Show the 3 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:50768
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Parent Cell Line:
| RW-4 (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Replacement of part of exon 1 containing the transcription start site with a PGK-neomycin cassette (J:50768)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Fgf10 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:50768
Min H et al.,
"Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless."
Genes Dev 1998 Oct 15;12(20):3156-61
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All: |
31 reference(s)
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Analysis Tools
