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| Nomenclature |
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Symbol:
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B2mtm1Jae
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Name:
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beta-2 microglobulin;
targeted mutation 1, Rudolf Jaenisch
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MGI ID: |
MGI:1927183 |
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Synonyms: |
B2M-, beta2M-, beta2mnull, MHC classI- |
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Gene:
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B2m
Location:
Chr2:122147686-122153083 bp, + strand
Genetic Position: Chr2,
60.55 cM, cytoband F1-F3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:65613
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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A neomycin resistance cassette was inserted into the second exon. (J:65613, J:80910)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:65613
Zijlstra M et al.,
"Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells."
Nature 1989 Nov 23;342(6248):435-8
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All: |
177 reference(s)
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Analysis Tools
