|
|
| Nomenclature |
|
Symbol:
|
Crebbptm1Dli
|
|
Name:
|
CREB binding protein;
targeted mutation 1, David Livingston
|
|
MGI ID: |
MGI:1926888 |
|
Synonyms: |
CBP- |
|
Gene:
|
Crebbp
Location:
Chr16:4084048-4213404 bp, - strand
Genetic Position: Chr16,
2.4 cM
|
|
Mutation origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:60630
|
|
Parent Cell Line:
| TC1/TC-1 (ES Cell) |
|
Strain of Origin:
|
129S6/SvEvTac
|
|
Mutation description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Replacement of two exons encoding the CH1 domain of the Crebbp gene with a neomycin cassette. (J:60630)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:60630
Kung AL et al.,
"Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP."
Genes Dev 2000 Feb 1;14(3):272-7
|
|
All: |
8 reference(s)
|
|