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| Nomenclature |
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Symbol:
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Atmtm1Led
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Name:
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ataxia telangiectasia mutated homolog (human);
targeted mutation 1, Philip Leder
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MGI ID: |
MGI:1926875 |
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Synonyms: |
Atm - |
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Gene:
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Atm
Location:
Chr9:53439149-53536740 bp, - strand
Genetic Position: Chr9,
29.12 cM, cytoband C-D
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Cross section through seminiferous tubule of +/+ and Atmtm1Led/Atmtm1Led mice
Show the 1 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:36561
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Parent Cell Line:
| TC1/TC-1 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: A PGK-neomycin cassette was inserted into a coding exon of the mouse Atm gene. The insertion position corresponds to nt 5640 of the human ATM cDNA. (J:36561)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Atm Mutation:
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29 strains or lines available |
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| References |
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Original: |
J:36561
Elson A et al.,
"Pleiotropic defects in ataxia-telangiectasia protein-deficient mice."
Proc Natl Acad Sci U S A 1996 Nov 12;93(23):13084-9
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All: |
26 reference(s)
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Analysis Tools
