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| Nomenclature |
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Symbol:
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Tg(PTHLH)7Wmp
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Name:
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transgene insertion 7, William M Philbrick
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MGI ID: |
MGI:1926698 |
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Synonyms: |
K14-PTHrP |
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Transgene:
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Tg(PTHLH)7Wmp
Location:
unknown
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Dental phenotype of Pthlhtm1Hmk/Pthlhtm1Hmk mice rescued with Tg(Col2a1-PTHLH)2Ecw and Tg(PTHLH)7Wmp transgenes
Show the 1 image(s) involving this allele.
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Transgene
origin |
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Strain of Origin:
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Not Specified
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: Overexpression of human parathyroid hormone-related peptide (PTHLH) in basal epidermis and outer root sheath of hair follicles driven by the human K14 (KRT14) promoter. (J:65403)
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Inheritance: | |
Not Specified |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Notes |
Transgenic mice derived from an additional founder, designated line 6, was described as having an identical phenotype.
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| References |
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Original: |
J:65043
Wysolmerski JJ et al.,
"Overexpression of parathyroid hormone-related protein in the skin of transgenic mice interferes with hair follicle development."
Proc Natl Acad Sci U S A 1994 Feb 1;91(3):1133-7
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All: |
15 reference(s)
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Analysis Tools
