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| Nomenclature |
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Symbol:
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Gfra2tm1Msa
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Name:
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glial cell line derived neurotrophic factor family receptor alpha 2;
targeted mutation 1, Matti S Airaksinen
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MGI ID: |
MGI:1926440 |
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Synonyms: |
Gfra2-, Gfralpha-2-, Gfralpha2-, GFRalpha2-KO |
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Gene:
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Gfra2
Location:
Chr14:70890130-70979838 bp, + strand
Genetic Position: Chr14,
36.79 cM, cytoband D3-E1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:53284
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Replacement of part of first coding exon of the gene with PGK-neomycin cassette. (J:53284)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gfra2 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:53284
Rossi J et al.,
"Retarded growth and deficits in the enteric and parasympathetic nervous system in mice lacking GFR alpha2, a functional neurturin receptor."
Neuron 1999 Feb;22(2):243-52
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All: |
16 reference(s)
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Analysis Tools
