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| Nomenclature |
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Symbol:
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Atmtm1Bal
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Name:
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ataxia telangiectasia mutated homolog (human);
targeted mutation 1, David Baltimore
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MGI ID: |
MGI:1926343 |
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Synonyms: |
ATM- |
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Gene:
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Atm
Location:
Chr9:53439149-53536740 bp, - strand
Genetic Position: Chr9,
29.12 cM, cytoband C-D
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Electron micrographs of wild type and Atmtm1Bal/Atmtm1Bal Purkinje neurons
Show the 4 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:42324
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Part of an exon encoding the kinase-conserved sequence of Atm and the following 3' exon was replaced with a PGK-neomycin cassette. (J:42324)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:42324
Xu Y et al.,
"Dual roles of ATM in the cellular response to radiation and in cell growth control [see comments]"
Genes Dev 1996 Oct 1;10(19):2401-10
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All: |
11 reference(s)
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Analysis Tools
