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| Nomenclature |
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Symbol:
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Tcf7tm1Cle
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Name:
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transcription factor 7, T cell specific;
targeted mutation 1, Hans Clevers
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MGI ID: |
MGI:1926298 |
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Synonyms: |
Tcf-1-, Tcf1-, Tcf1Hom, Tcf7-, TcfdeltaVII |
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Gene:
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Tcf7
Location:
Chr11:52252371-52283014 bp, - strand
Genetic Position: Chr11,
31.86 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:23255
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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A 67-bp fragment encoding exon VII was replaced with a neomycin cassette. (J:23255)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Tcf7 Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:23255
Verbeek S et al.,
"An HMG-box-containing T-cell factor required for thymocyte differentiation."
Nature 1995 Mar 2;374(6517):70-4
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All: |
29 reference(s)
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