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Tcf7tm1Cle
Targeted Allele Detail

Nomenclature
Symbol: Tcf7tm1Cle
Name: transcription factor 7, T cell specific; targeted mutation 1, Hans Clevers
MGI ID: MGI:1926298
Synonyms: Tcf-1-, Tcf1-, Tcf1Hom, Tcf7-, TcfdeltaVII
Gene: Tcf7   Location: Chr11:52252371-52283014 bp, - strand    Genetic Position: Chr11, 31.86 cM
Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:23255
Parent Cell Line: E14 (ES Cell)
Strain of Origin: 129P2/OlaHsd
Mutation
description
Allele Type:   Targeted (knock-out)
Mutations:   Insertion, Intragenic deletion
    A 67-bp fragment encoding exon VII was replaced with a neomycin cassette. (J:23255)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcf7 Mutation: 7 strains or lines available
References
Original: J:23255 Verbeek S et al., "An HMG-box-containing T-cell factor required for thymocyte differentiation." Nature 1995 Mar 2;374(6517):70-4
All: 29 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/08/2013
MGI 5.13
The Jackson Laboratory