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| Nomenclature |
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Symbol:
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E2f5tm1Dli
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Name:
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E2F transcription factor 5;
targeted mutation 1, David M Livingston
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MGI ID: |
MGI:1926192 |
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Synonyms: |
E2F-5- |
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Gene:
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E2f5
Location:
Chr3:14578671-14606308 bp, + strand
Genetic Position: Chr3,
3.1 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:47283
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Parent Cell Line:
| CJ7 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The two exons encoding the carboxy-terminal half of the DNA-binding and the leucine zipper domains were replaced with a neomycin resistance gene. (J:47283)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:47283
Lindeman GJ et al.,
"A specific, nonproliferative role for E2F-5 in choroid plexus function revealed by gene targeting."
Genes Dev 1998 Apr 15;12(8):1092-8
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All: |
3 reference(s)
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Analysis Tools
