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| Nomenclature |
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Symbol:
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Cdkn1btm1Ako
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Name:
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cyclin-dependent kinase inhibitor 1B;
targeted mutation 1, Andrew Koff
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MGI ID: |
MGI:1888808 |
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Synonyms: |
Cdkn1btm1Kiyo, P27-, p27D51, p27delta, p27Kip1, p27Kip1 -, p27/Kip1- |
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Gene:
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Cdkn1b
Location:
Chr6:134920401-134925513 bp, + strand
Genetic Position: Chr6,
65.77 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:33401
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Parent Cell Line:
| CJ7 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: Insertion of a neomycin cassette into the first coding exon of the Cdkn1b gene. Allele produces an N-terminal partial protein product which authors refer to as delta51. (J:33401)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cdkn1b Mutation:
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9 strains or lines available |
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| References |
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Original: |
J:33401
Kiyokawa H et al.,
"Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1)."
Cell 1996 May 31;85(5):721-32
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All: |
63 reference(s)
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Analysis Tools
