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| Nomenclature |
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Symbol:
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Nf2tm1Gth
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Name:
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neurofibromatosis 2;
targeted mutation 1, Gilles Thomas
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MGI ID: |
MGI:1888776 |
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Synonyms: |
Nf2KO3 |
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Gene:
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Nf2
Location:
Chr11:4765845-4849536 bp, - strand
Genetic Position: Chr11,
3.0 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:63264
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Parent Cell Line:
| IB10/E14IB10 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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A IRES-lacZ-PGK-hygromycin resistance cassette was inserted into exon 3 of the gene. (J:63264)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:63264
Giovannini M et al.,
"Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2."
Genes Dev 2000 Jul 1;14(13):1617-30
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All: |
7 reference(s)
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Analysis Tools
