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| Nomenclature |
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Symbol:
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Psaptm1Suz
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Name:
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prosaposin;
targeted mutation 1, Kunihiko Suzuki
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MGI ID: |
MGI:1888378 |
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Synonyms: |
PS-, SAP- |
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Gene:
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Psap
Location:
Chr10:60277627-60302594 bp, + strand
Genetic Position: Chr10,
30.02 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:33477
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Parent Cell Line:
| BK4 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 3 was disrupted by the insertion of a neomycin selection cassette. Northern blot analysis of tissues obtained from homozygous mutant mice showed an absence of transcript. (J:33477)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:33477
Fujita N et al.,
"Targeted disruption of the mouse sphingolipid activator protein gene: a complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids."
Hum Mol Genet 1996 Jun;5(6):711-25
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All: |
18 reference(s)
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Analysis Tools
