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| Nomenclature |
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Symbol:
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Itgb7tm1Cgn
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Name:
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integrin beta 7;
targeted mutation 1, University of Cologne
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MGI ID: |
MGI:1861953 |
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Synonyms: |
beta7-, Itgbtm1Ctg |
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Gene:
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Itgb7
Location:
Chr15:102215995-102231935 bp, - strand
Genetic Position: Chr15,
57.39 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:34306
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Parent Cell Line:
| BL/6-III (ES Cell) |
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Strain of Origin:
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C57BL/6J
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance cassette replaced part of exon 12 and all of exons 13 and 14, which encode the transmembrane and part of the extracellular domains. (J:34306)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:34306
Wagner N et al.,
"Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue."
Nature 1996 Jul 25;382(6589):366-70
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All: |
34 reference(s)
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