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| Nomenclature |
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Symbol:
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Il4ratm1Sz
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Name:
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interleukin 4 receptor, alpha;
targeted mutation 1, Leonard Shultz
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MGI ID: |
MGI:1861951 |
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Synonyms: |
IL-4R-, IL-4Ralpha-, Il-4ralphatm1Sz, Il4ratm1, IL-4R KO |
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Gene:
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Il4ra
Location:
Chr7:125552282-125579472 bp, + strand
Genetic Position: Chr7,
68.94 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:43656
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Parent Cell Line:
| BALB/c-I (ES Cell) |
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Strain of Origin:
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BALB/cJ
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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A neomycin resistance cassette replaced exons 7 - 9 of the gene. (J:43656)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:43656
Noben-Trauth N et al.,
"An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice."
Proc Natl Acad Sci U S A 1997 Sep 30;94(20):10838-43
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All: |
92 reference(s)
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Analysis Tools
