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| Nomenclature |
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Symbol:
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Trp63tm1Brd
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Name:
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transformation related protein 63;
targeted mutation 1, Allan Bradley
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MGI ID: |
MGI:1861713 |
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Synonyms: |
p63Brdm1 |
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Gene:
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Trp63
Location:
Chr16:25683763-25892102 bp, + strand
Genetic Position: Chr16,
17.37 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:54636
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Parent Cell Line:
| AB2.2 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprtb-m2
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: An integration vector disrupts the reading frame within exon 6. Northern blot analysis on homozygous mutant animals indicates that an mRNA transcript is not produced from this allele. (J:54636)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Trp63 Mutation:
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10 strains or lines available |
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| References |
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Original: |
J:54636
Mills AA et al.,
"p63 is a p53 homologue required for limb and epidermal morphogenesis."
Nature 1999 Apr 22;398(6729):708-13
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All: |
10 reference(s)
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Analysis Tools
