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| Nomenclature |
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Symbol:
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Cdh2tm1Hyn
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Name:
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cadherin 2;
targeted mutation 1, Richard Hynes
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MGI ID: |
MGI:1861181 |
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Synonyms: |
Cdh2-, N-cadherin- |
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Gene:
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Cdh2
Location:
Chr18:16588877-16809246 bp, - strand
Genetic Position: Chr18,
10.1 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:37888
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: A neomycin cassette was inserted into the exon 10, which encodes part of the extracellular domain of the protein. The protein was untectectable in Western blots of protein lysates derived from homozygous mutant embryos. (J:37888)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:37888
Radice GL et al.,
"Developmental defects in mouse embryos lacking N-cadherin."
Dev Biol 1997 Jan 1;181(1):64-78
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All: |
13 reference(s)
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Analysis Tools
