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| Nomenclature |
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Symbol:
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Il1r1tm1Imx
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Name:
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interleukin 1 receptor, type I;
targeted mutation 1, Immunex Research and Development Corporation
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MGI ID: |
MGI:1861112 |
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Synonyms: |
IL-1R-, IL-1R1-, Il1r1tm1jmx, IL-1RI KO, Il1rtm1Imx, IL-R1-, RIko |
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Gene:
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Il1r1
Location:
Chr1:40225080-40316177 bp, + strand
Genetic Position: Chr1,
18.81 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:43088
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Parent Cell Line:
| AB1 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprt+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance cassette replaced two exons of the gene, which encode amino acids 4 - 225 of the mature protein. (J:43088)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:43088
Glaccum MB et al.,
"Phenotypic and functional characterization of mice that lack the type I receptor for IL-1."
J Immunol 1997 Oct 1;159(7):3364-71
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All: |
151 reference(s)
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Analysis Tools
