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| Nomenclature |
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Symbol:
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Myo7ash1-6J
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Name:
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myosin VIIA;
shaker 1, 6 Jackson
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MGI ID: |
MGI:1860092 |
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Synonyms: |
Myo7a6J, sh6J |
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Gene:
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Myo7a
Location:
Chr7:98051060-98119524 bp, - strand
Genetic Position: Chr7,
53.57 cM
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Mutation
origin |
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Strain of Origin:
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BKS.Cg-Dock7m Leprdb
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Single point mutation |
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Mutation details: A G-to-C transversion mutation is predicted to result in an arginine to proline change at position 241 in the encoded protein. This mutation is predicted to lie within the head domain of the protein. Northern blot analysis indicated that mRNA expression, size, and stability were unaffected. Immunoblot analysis showed that approximately 20% of the normal level of the protein was expressed. (J:23257)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:17340
Letts VA et al.,
"Remutation at the shaker-1 locus"
Mouse Genome 1994;92(1):116
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All: |
7 reference(s)
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Analysis Tools
