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| Nomenclature |
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Symbol:
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Tfrctm1Nca
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Name:
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transferrin receptor;
targeted mutation 1, Nancy C Andrews
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MGI ID: |
MGI:1859944 |
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Synonyms: |
Trfr- |
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Gene:
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Tfrc
Location:
Chr16:32608920-32632794 bp, + strand
Genetic Position: Chr16,
23.06 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:54107
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Coding sequence including exons 3 through 5 was replaced with a neomycin selection cassette. (J:54107)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:54107
Levy JE et al.,
"Transferrin receptor is necessary for development of erythrocytes and the nervous system."
Nat Genet 1999 Apr;21(4):396-9
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All: |
2 reference(s)
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