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Tfrctm1Nca
Targeted Allele Detail

Nomenclature
Symbol: Tfrctm1Nca
Name: transferrin receptor; targeted mutation 1, Nancy C Andrews
MGI ID: MGI:1859944
Synonyms: Trfr-
Gene: Tfrc   Location: Chr16:32608920-32632794 bp, + strand    Genetic Position: Chr16, 23.06 cM
Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:54107
Parent Cell Line: J1 (ES Cell)
Strain of Origin: 129S4/SvJae
Mutation
description
Allele Type:   Targeted (knock-out)
Mutations:   Insertion, Intragenic deletion
    Coding sequence including exons 3 through 5 was replaced with a neomycin selection cassette. (J:54107)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tfrc Mutation: 16 strains or lines available
References
Original: J:54107 Levy JE et al., "Transferrin receptor is necessary for development of erythrocytes and the nervous system." Nat Genet 1999 Apr;21(4):396-9
All: 2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/08/2013
MGI 5.13
The Jackson Laboratory