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| Nomenclature |
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Symbol:
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Trp73tm1Fmc
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Name:
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transformation related protein 73;
targeted mutation 1, Frank McKeon
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MGI ID: |
MGI:1859911 |
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Synonyms: |
p73 - |
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Gene:
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Trp73
Location:
Chr4:154056253-154140208 bp, - strand
Genetic Position: Chr4,
83.79 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:60896
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 5 and a portion of exon 6, encoding part of the DNA binding domain, and the neighboring intronic sequences were replaced by a neomycin gene. (J:60896)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Trp73 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:60896
Yang A et al.,
"p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours."
Nature 2000 Mar 2;404(6773):99-103
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All: |
22 reference(s)
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Analysis Tools
