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| Nomenclature |
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Symbol:
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Fgf10tm1Ska
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Name:
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fibroblast growth factor 10;
targeted mutation 1, Shigeaki Kato
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MGI ID: |
MGI:1859647 |
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Synonyms: |
fgf10- |
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Gene:
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Fgf10
Location:
Chr13:118669791-118792115 bp, + strand
Genetic Position: Chr13,
67.14 cM, cytoband A3-A4
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Submandibular gland abnormalities in Fgf10tm1Ska/Fgf10tm1Ska and Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn mice at E12.5
Show the 3 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:51966
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Parent Cell Line:
| TT2 (ES Cell) |
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Strain of Origin:
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(C57BL/6NCrlj x CBA/JNCrlj)F1
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance cassette replaced 1.1 kb of sequence that contains the exon encoding the ATG translation initiation site and the amino terminal 110 amino acids of the encoded protein. (J:51966)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Fgf10 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:51966
Sekine K et al.,
"Fgf10 is essential for limb and lung formation."
Nat Genet 1999 Jan;21(1):138-41
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All: |
47 reference(s)
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Analysis Tools
