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| Nomenclature |
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Symbol:
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Map3k14aly
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Name:
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mitogen-activated protein kinase kinase kinase 14;
alymphoplasia
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MGI ID: |
MGI:1858522 |
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Synonyms: |
aly, nikaly |
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Gene:
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Map3k14
Location:
Chr11:103219762-103267472 bp, - strand
Genetic Position: Chr11,
66.8 cM
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Mutation
origin |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Single point mutation |
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Mutation details: A G-to-A transition point mutation resulted in a replacement of a conserved glycine for an arginine at position 855 of the encoded protein. (J:54529)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Map3k14 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:16865
Miyawaki S et al.,
"A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice."
Eur J Immunol 1994 Feb;24(2):429-34
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All: |
80 reference(s)
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Analysis Tools
