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| Nomenclature |
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Symbol:
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Msh2tm1Htr
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Name:
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mutS homolog 2 (E. coli);
targeted mutation 1, Hein Te Riele
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MGI ID: |
MGI:1858055 |
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Synonyms: |
Msh2-, Msh2tm1Nki |
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Gene:
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Msh2
Location:
Chr17:87672330-87723713 bp, + strand
Genetic Position: Chr17,
57.87 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:27469
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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A hygromycin resistance cassette was inserted between codons 588 and 589 of the gene. (J:27469)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Msh2 Mutation:
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44 strains or lines available |
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| References |
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Original: |
J:27469
de Wind N et al.,
"Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer."
Cell 1995 Jul 28;82(2):321-30
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All: |
42 reference(s)
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Analysis Tools
