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| Nomenclature |
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Symbol:
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Mlh1tm1Rak
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Name:
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mutL homolog 1 (E. coli);
targeted mutation 1, Raju Kucherlapati
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MGI ID: |
MGI:1858054 |
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Synonyms: |
mlh1-, Mlh1-, Mlh1delsta |
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Gene:
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Mlh1
Location:
Chr9:111228228-111271608 bp, - strand
Genetic Position: Chr9,
60.92 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:33878
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Parent Cell Line:
| E14.1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
| |
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Replacement of exon 2 and flanking intronic sequence with a neomycin cassette. (J:33878)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:33878
Edelmann W et al.,
"Meiotic pachytene arrest in MLH1-deficient mice."
Cell 1996 Jun 28;85(7):1125-34
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All: |
26 reference(s)
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Analysis Tools
