Ctnnb1<tm1Mmt> Targeted Allele Detail MGI Mouse (MGI:1858008)

Ctnnb1^tm1Mmt
Targeted Allele Detail

Nomenclature

Symbol:	Ctnnb1^tm1Mmt
Name:	catenin (cadherin associated protein), beta 1; targeted mutation 1, Makoto M Taketo
MGI ID:	MGI:1858008
Synonyms:	B-catenin^fl3, BcatGOF, beta-cat^act, beta-catenin^deltaex3, beta-catenin^lox-ex3, beta-catenin^loxEx3, beta-catenin/loxP(ex3), beta-cat^ex3, beta-cat^gof, beta-cat^loxEx3, Catnb^(ex3)fl, Catnb^(Flox3, Catnb^lox(ex3), Catnb^tm1Tak, Ctnnb1^ex3, Ctnnb1^(Ex3)fl, Ctnnb1^f(Ex3), Ctnnb1^lox(ex3), Ctnnb^llox(ex3), Ctnnb^lox(ex3), GOF
Gene:	Ctnnb1 Location: Chr9:120929216-120960507 bp, + strand Genetic Position: Chr9, 72.19 cM

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:58367
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Mutation
description

Phenotypes

View phenotypes for all genotypes (concatenated display).

Disease models

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)

Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Ctnnb1 Mutation:	12 strains or lines available

Notes

Phenotypic Similarity to Human Syndrome: Melanoma J:155731

Phenotypic Similarity to Human Syndrome: Granulosa cell tumor of the testis (GCTT) J:149060

Phenotypic Similarity to Human Syndrome: Granulosa cell tumor (GCT) J:142150

Phenotypic Similarity to Human Syndrome: Granulosa cell tumor (GCT) J:186144

Phenotypic Similarity to Human Syndrome: Granulosa cell tumor of the testis (GCTT) J:186144

References

Original:	J:58367 Harada N et al., "Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene." EMBO J 1999 Nov 1;18(21):5931-42
All:	202 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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