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| Nomenclature |
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Symbol:
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Pou3f4tm1Tno
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Name:
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POU domain, class 3, transcription factor 4;
targeted mutation 1, T Noda
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MGI ID: |
MGI:1857991 |
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Synonyms: |
Brn-4- |
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Gene:
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Pou3f4
Location:
ChrX:110814280-110817855 bp, + strand
Genetic Position: ChrX,
48.2 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:57298
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A PGK-neomycin resistance cassette replaced the coding region of this gene. Protein from homozygous mutant animals lacked DNA binding activity as determined by gel mobility shift assays. (J:57298)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Pou3f4 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:57298
Minowa O et al.,
"Altered cochlear fibrocytes in a mouse model of DFN3 nonsyndromic deafness [see comments]"
Science 1999 Aug 27;285(5432):1408-11
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All: |
4 reference(s)
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Analysis Tools
