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| Nomenclature |
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Symbol:
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Pou3f4tm1Cren
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Name:
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POU domain, class 3, transcription factor 4;
targeted mutation 1, Bryan Crenshaw III
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MGI ID: |
MGI:1857990 |
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Synonyms: |
Brn4- |
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Gene:
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Pou3f4
Location:
ChrX:110814280-110817855 bp, + strand
Genetic Position: ChrX,
48.2 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:56294
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A lacZ reporter gene and a PGK-neomycin resistance cassette replaced the entire intronless coding region and a small region of 3'-flanking sequences. (J:56294)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Pou3f4 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:56294
Phippard D et al.,
"Targeted mutagenesis of the POU-domain gene Brn4/Pou3f4 causes developmental defects in the inner ear."
J Neurosci 1999 Jul 15;19(14):5980-9
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All: |
5 reference(s)
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Analysis Tools
